If you’re searching for a crowd-pleasing, comforting dinner that bursts with hearty flavors and plenty of melty cheese, this MEXICAN CASSEROLE is about to become your new favorite! Imagine savory layers of seasoned beef, creamy beans, tangy Ro-tel tomatoes, and crunchy tortilla chips, all brought together under a bubbly blanket of cheddar. It’s the ultimate weeknight hero: quick to pull together, endlessly adaptable, and sure to put smiles on the faces of everyone at your table.

Ingredients You’ll Need
The magic of this MEXICAN CASSEROLE lies in how a few pantry staples transform into a flavor-packed family meal. Each ingredient plays a crucial role—adding spice, creaminess, crunch, or that irresistible cheesy pull.
- Lean ground beef: Offers hearty flavor and protein as the casserole’s foundation—feel free to swap in ground turkey or chicken if you like!
- Ranch Style beans: This classic Tex-Mex ingredient brings a slightly smoky, perfectly seasoned twist.
- Tortilla chips, crushed: Add crunch and act as handy layers, holding everything together—use your favorite brand for best flavor.
- Ro-tel tomatoes: These zesty tomatoes with green chilies amp up the flavor with a gentle kick.
- Small onion, chopped: Sautéed onions weave in delicious sweetness and bite.
- Shredded cheddar cheese, divided: Melts into gooey layers—use extra sharp for more punch!
- Taco seasoning packet: Infuses the casserole with classic Mexican spice and warmth.
- Cream of chicken soup: Adds creamy richness that ties all the ingredients together into pure comfort food.
- Water: Helps mix everything smoothly so the casserole bakes up just right.
- Sour cream and salsa for serving: The finishing touch that brings fresh, cool, and tangy notes.
How to Make MEXICAN CASSEROLE
Step 1: Prepare the Meat Mixture
Start by preheating your oven to 325 degrees. In a large skillet over medium-high heat, cook the ground beef until nicely browned, breaking it into crumbles as you go. Once it’s cooked through, drain off any excess fat to keep things light and flavorful.
Step 2: Build the Flavor Base
With your beef browned, stir in the Ranch Style beans, Ro-tel tomatoes, chopped onion, taco seasoning, cream of chicken soup, and 1/2 cup of water. Mix everything together well, letting it simmer on medium-low heat so all those zesty, savory flavors can mingle and get cozy. This step sets the stage for a truly irresistible MEXICAN CASSEROLE.
Step 3: Layer the Casserole
Lightly grease a 9×13-inch casserole dish to make serving (and cleanup!) a breeze. Start your first layer with plenty of crushed tortilla chips—enough to cover the bottom but not so much it becomes dry. Next, spoon on half of your rich, beefy mixture, then sprinkle over half of the shredded cheddar for that gooey, melty magic. Repeat the layers one more time so every bite is stacked with goodness.
Step 4: Bake Until Bubbly
Cover your masterpiece with foil and slide it into the oven. Bake for 20 to 30 minutes, until it’s piping hot and the cheese is melted and bubbling at the edges. The anticipation is totally worth it!
Step 5: Rest and Serve
Once the casserole is out of the oven, be patient and let it sit for 5 to 10 minutes. This short pause helps everything set up so each slice holds its shape. Finish by topping with cool sour cream and your favorite salsa, then dig in!
How to Serve MEXICAN CASSEROLE

Garnishes
Fresh toppings can take your MEXICAN CASSEROLE to the next level. Try a generous dollop of sour cream, some freshly chopped cilantro, sliced green onions, or maybe even a handful of diced tomatoes. Don’t forget your favorite jarred or homemade salsa—whether you like it mild or fiery, the contrast is delicious!
Side Dishes
To round out your meal, serve the casserole alongside a crisp green salad tossed with lime vinaigrette—or maybe simple black beans and rice for extra heartiness. Freshly sliced avocado or guacamole adds a creamy, cooling compliment to the warm, cheesy casserole.
Creative Ways to Present
For potlucks or parties, spoon the MEXICAN CASSEROLE into individual ramekins for single servings. Or, offer a build-your-own bar with extra garnishes—everyone can customize their plate just how they like it. Cutting leftovers into squares and packing them for lunch is not only practical, but guarantees a midday treat!
Make Ahead and Storage
Storing Leftovers
Leftover MEXICAN CASSEROLE is a lifesaver for busy lunches or after-school snacks. Simply cover the baking dish tightly with foil or transfer leftovers to an airtight container. They’ll keep fresh in the fridge for up to 3 days and reheat beautifully.
Freezing
This casserole is freezer-friendly! Allow it to cool completely, then wrap well in plastic wrap and a layer of foil, or store in a freezer-safe container. For best results, freeze for up to two months. Thaw overnight in the refrigerator before reheating.
Reheating
To bring your casserole back to its cheesy, bubbly best, reheat portions in the oven at 325 degrees for about 15-20 minutes, or until warmed through. In a pinch, the microwave works too—just use short bursts to keep the chips from getting soggy.
FAQs
Can I use a different type of meat?
Absolutely! While ground beef is classic for this MEXICAN CASSEROLE, ground turkey, chicken, or even a vegetarian meat substitute can be used. Adjust seasonings as needed to suit your taste.
What if I can’t find Ranch Style beans?
No worries—substitute with pinto beans or black beans, and add a pinch more taco seasoning or a dash of chili powder to boost the flavor.
Is there a gluten-free option?
Yes! Double-check your taco seasoning, soup, and chips to make sure they’re gluten-free. Most of the other ingredients are already safe for gluten-free diets.
Can I add vegetables?
Definitely! Feel free to fold in some corn, diced bell peppers, or even zucchini into the beef mixture for extra color and nutrition. It’s a great way to sneak in more veggies!
How can I make it spicier?
To turn up the heat in your MEXICAN CASSEROLE, swap in hot Ro-tel, add fresh jalapeños, or sprinkle in some crushed red pepper flakes. Customize the spice level to match your family’s preferences.
Final Thoughts
This MEXICAN CASSEROLE is the kind of dish that brings everyone together, fills the house with delicious aromas, and makes dinner feel special—no matter the night. Give it a try and enjoy a little Tex-Mex comfort that’s as easy as it is unforgettable. I hope it earns a regular spot on your table!
PrintMEXICAN CASSEROLE Recipe
This Mexican Casserole is a delicious and hearty dish that combines layers of seasoned ground beef, beans, cheese, and tortilla chips. Perfect for a comforting family meal or a crowd-pleasing dinner.
- Prep Time: 15 minutes
- Cook Time: 30 minutes
- Total Time: 45 minutes
- Yield: 8 servings
- Category: Main Dish
- Method: Baking
- Cuisine: Mexican
- Diet: Gluten Free
Ingredients
Ground Beef Mixture:
- 1 pound lean ground beef
- 1 can Ranch Style beans
- 1 can Ro-tel tomatoes
- 1 small onion, chopped
- 1 package taco seasoning
- 1 can cream of chicken soup
- 1/2 cup water
Additional Ingredients:
- 1 10-12 ounce bag tortilla chips, crushed (amount as desired)
- 2 cups shredded cheddar cheese, divided
- Sour cream and salsa for serving
Instructions
- Preheat Oven: Preheat the oven to 325 degrees Fahrenheit.
- Prepare Meat Mixture: Brown the ground beef in a skillet, drain off excess fat, then add beans, tomatoes, onion, taco seasoning, soup, and water. Simmer until heated through.
- Assemble Casserole: Grease a 9×13 casserole dish. Layer crushed tortilla chips, the meat/bean mixture, and cheddar cheese. Repeat the layers.
- Bake: Cover the dish with foil and bake for 20-30 minutes, or until bubbly.
- Serve: Let it cool for 5-10 minutes before serving. Top with sour cream and salsa.
Notes
- This casserole can be customized with additional toppings like sliced jalapenos, olives, or avocado.
- Feel free to use your favorite type of beans or add extra vegetables for more flavor.
Nutrition
- Serving Size: 1 serving
- Calories: 380
- Sugar: 3g
- Sodium: 870mg
- Fat: 20g
- Saturated Fat: 8g
- Unsaturated Fat: 10g
- Trans Fat: 0g
- Carbohydrates: 28g
- Fiber: 3g
- Protein: 23g
- Cholesterol: 70mg